About us

Ametis JSC was founded on June 25, 1998 in Blagoveshchensk, Amur region. Despite the fact that Ametis JSC is relatively young company, but has already become the largest industrial complex in production of larch extracts and showed itself as a stable, with a reputation of quality and competitive prices.

All activities of the company are submitted to one aim: to create the high-tech manufacturing enterprise by complex processing of Dahurian Larch wood for the purpose of unique natural substances extraction.

The company doesn’t rest on its laurels and develops successfully in the domestic and international markets, improving technology of production, introducing know-how to produce natural, highly effective, quality products. In this regard, Ametis JSC works closely with more than 20 leading scientific institution located in Russia, including Amur State Medical Academy, Far East State Agrarian University, Institutes of Tomsk, Novosibirsk and Moscow.

Company profile in PDF format

Feed additives

Feed additive Ecostimul-2

  • Has a prophylactic effect against ketosis in dairy cows;
  • Promotes the preservation of livestock, increases the survival of baby animals;
  • Regulates metabolic processes , has a positive effect on the functional state of the internal organs and systems;
  • Creates the mechanisms of cells protection against the viral and bacterial pathologies by neutralizing the activity of free radicals;
  • Stimulate the fertility queen bees;
  • Increases the productivity of honey bee colonies;

Increases the antioxidant status of the organism.

Composition:

  • dihydroquercetin (NLT 70%);
  • other relative bioflavonoids.

Feed additive EcoKor

  • Has a prophylactic effect against ketosis (reduces the ketone bodies in milk and blood);
  • Increases milk yield;
  • Promotes the preservation of livestock, increases the survival of baby animals;
  • Maintains the cow health and productivity;
  • Increases the antioxidant status of the organism;
  • Improves the metabolism;
  • Prevents the disorders of carbohydrate and lipid metabolism, osteodystophy, fatty liver infiltration.

Composition:

  • «Ecostimul-2»
  • Powerful antioxidant, inhibits free radical lipid oxidation, prevents the destruction of cell membranes, improves blood microcirculation.
  • 60% Choline chloride
  • Takes part in tissues formation of animal bodies, in particular, in maintaining membrane stability.
  • 18% L-carnitine
  • Performs important functions in energy metabolism in ruminant animals.

Dietary supplements

Dietary supplement Laviocard+

Effect of Laviocard +

  • Strengthens blood vessels and capillary walls, increasing their strength and elasticity. Restores blood microcirculation in the body;
  • Prevents formation of thrombus which are the causes of many cardiovascular diseases;
  • Lowers blood viscosity and impacts blood coagulation, weakens red blood cell aggregation, improves their deformability during conditions characterized by increased blood viscosity (cerebro-ischemia, cardio ischemia, arterial hypertension, diabetes);
  • Prevents the appearance of inflammatory processes in the body, has anti-oedematous activity, lowers levels of cholesterol and lipids in the liver and blood plasma;
  • Protects neurons from oxidative stress, one of the main causes of degenerative brain diseases, including Parkinson’s disease and Alzheimer’s disease;
  • Slows down body’s aging processes;
  • Lowers the risk of progressive, diabetes-related complications of blood vessels due to its positive impact on the vessel permeability and its ability to lower thrombosis formation;
  • Inhibits the activity of gualuronidase, the enzyme that damages blood vessels.

Recommended use of Laviocard+

As a complex therapy of cardiovascular diseases:

  • Atherosclerosis. Taking “Laviocard+” together with course of medical treatment the concentration of cholesterol and its atherogenic fractions is reduced as well as the coefficient of atherogeneity of blood plasma, the level of triglyceride goes lower in blood, that favours the reduction of atherosclerosis development.
  • Ischemic heart disease, impaired cardial function, rhythm heart disturbance. “Laviocard+” promotes improvement rheological blood properties as well as the condition of erythrocytes, improves its deformability and hemodynamic characteristics.
  • Arterial hypertension I, II types. “Laviocard+” helps to normalize the blood pressure, decrease it daily fluctuation range, improves vessels tone and cerebral blood flow.
  • As a prophylaxis and in the period of rehabilitation after having an infarction and stroke. The complex “Laviocard+” restores the microcirculation, favours the improvement of venous drainage, decreases the hypoxemia, has an influence on metabolism in cells.

As a prophylactic remedy:

  • Varicose diseases, phlebothrombosis, postthrombophlebitic syndrome. For venous walls strengthening, venous blood flow improvement, prevention of thrombosis formation and edema reduction. The course of medical treatment by the complex “Laviocard+” could help to decrease the intensity of “varicose veins”.
  • Complications of pancreatic diabetes. Is used for microcirculation improvement, strengthening of capillary channel, decreasing of insulin resistance. The quality of life is improved.
  • Worsening and complication of inflammation. Improves the resistibility, decreases the evidence of inflammation, prevents the exacerbation and chronic inflammatory diseases.

Contra-indication: individual intolerance of ingredients, pregnant or lactating woman

Ingredients:

  • Lavitol (Dihydroquercetin) – 30 mg
  • Ascorbic acid – 70 mg
  • Lactose as adjuvant

Dietary supplement “VitaLAG”

As a complex therapy of gastrointestinal and immune system disorders:

  • Dysbacteriosis: improves nutrition and growth of bifidobacteria and lactobacilli, promotes better disintegration, nutritive absorption and digestion in the gastrointestinal tract.
  • Gastric and duodenal ulcer: taking VitaLAG together with course of traditional medical treatment contributes to a more rapid and effective reduction of pain syndrome, dyspeptic disorders (sickness, vomiting, heartburn, appetite disturbance, meteorism). VitaLAG has a protective effect on the mucous membrane, promoting healing of gastric and duodenal ulcers.
  • Gastritis: VitaLAG improves regeneration of the gastric mucosa, reduces the intensity of inflammatory processes.
  • Immune system disorders: VitaLAG is recommended as the fortifying agent for improving the protective potency of the organism, resistance to infectious diseases and harmful environmental effects.

As a prophylactic remedy:

  • Worsening and complication of inflammation. Improves the resistibility, decreases the evidence of inflammation, prevents the exacerbation and chronic inflammatory diseases.
  • Cardiovascular diseases: VitaLAG helps normalize blood pressure, improves blood microcirculation and cerebral circulation, reduces the effects of hypoxia and ischemia.

Ingredients:

  • Lavitol-arabinogalactan — 260 mg,
  • Lavitol (Dihydroquercetin) — 30 mg

Contra-indication: individual intolerance of ingredients, pregnant or lactating woman

Dietary supplement Laviocard Extra

The main features of dietary supplement Laviocard Extra are the following:

  • own patented technology for of the extraction of Dihydroquercetin that guarantees the high quality of the supplement;
  • Laviocard Extra contains Lavitol (Dihydroquercetin) with the maximal content of Dihydroquercetin (99%) and high level of biological activity;
  • Laviocard Extra has been developed with due regard for the level of daily consumption of vitamin C (from 70 up to 700 mg per a day) and dihydroquercetin (from 25 up to 100 mg per a day);
  • A unique combination of Vitamin C with Dihydroquercetin has a powerful synergistic effect that promotes the comprehensive protection of the cardiovascular system.

Laviocard Extra is recommended as a source of Dihydroquercetin and an additional source of Vitamin C.
Laviocard Extra was developed as a means to improve the functional status of the cardiovascular system, and as a complex therapy of hypertension.

Action of Dihydroquercetin in combination with Vitamin C as a complex therapy of cardiovascular diseases:

  • Arterial hypertension I, II types. Helps to normalize the blood pressure, decrease the appearance of headaches and giddiness.
  • Ischemic heart disease. Promotes improvement of functional status of the cardiovascular system and its physical endurance
  • As a prophylaxis and in the period of rehabilitation after having an infarction and stroke. Improves cerebral circulation and coronary vessels.

Contra-indication: individual intolerance of ingredients, pregnant or lactating woman
Ingredients:

  • Lavitol (Dihydroquercetin) with dihydroquercetin content 99% - 100 mg
  • Ascorbic acid – 70 mg

Raw Lavitol and by-products

Raw Lavitol

Raw Lavitol is the substance that is represented by mix of flavonoids (Dihydroquercetin and other relative flavonoids) and has the antioxidative properties. The content of Dihydroquercetin (taxifolin) ranges from 70% to 88%. Ametis JSC produces Raw Lavitol on the grounds of Technical Requirements TY 2455−001−48375962−03. Raw Lavitol could be used as the main compound of plant growth stimulants.

Moreover the purification of Raw Lavitol allows getting Dihydroquercetin with higher purity.

Larch oil Lavitol

Larch oil Lavitol is a by-product derived from Dahurian Larch (Larix gmelinii, Larix dahurica) by a combined processing method.

The chemical composition of the Larch oil is complex and various. It consists of the blend of terpene hydrocarbons, resin acids, phytosterols, tocopherols, diterpene and fatty acids, dihydroquercetin.

Organoleptic characteristics:

  • Appearance: Viscous oily fluid
  • Color: from golden yellow to light brown
  • Odor: wooden

Basic properties

Larch oil has high antiviral and biological activity; shows wound healing, antimicrobic and anti-burning effect. Besides, larch oil “Lavitol” is an effective antioxidant because of containing up to 20 % of dihydroquercetin.

Larch oil is perfectly combined with vegetable oils, vitamins, plant extracts and auxiliary components.

Larch resin Lavitol

Larch resin Lavitol is a by-product derived from Dahurian Larch (Larix gmelinii, Larix dahurica) by a combined processing method.

Physico-chemical characteristics

Larch resin Lavitol consists of hydrocarbons, carbonyl compounds, Primary diterpene-alcohol, microelements, phenocarboxylic and fatty acids, as well as dihydroquercetin.

  • Appearance: hard mass
  • Color: light brown to dark brown
  • Odor: strongly pronounced wood odor
  • Solubility: soluble in alcohol medium, ether, different kinds of solvents and in some oils, insoluble in water.
  • Density: 1.0-1.1 g/L
  • pH: 5-7

The resin softens when heated

Fields of application

Due to the unique chemical composition larch resin has antioxidant, antiseptic, capillary-protective, anti-inflammatory, antimicrobial, wound healing properties, it is successfully used in cosmetic and medical industries. Larch resin has the strong effect on the healing of posttraumatic wounds and burns, soft tissue bruise as well as on uninflammed trophic wounds. Larch resin is recommended as the basic compound of hot compresses and ointments intended for prevention of upper airways and joint diseases.

Larch resin is also used in production of cosmetic products: regenerating creams, SPF lotions and creams, moisurisers, lip cosmetics, etc. The studies, conducted on various emulsions with larch resin Lavitol, confirmed the possibility of introduction the larch resin in the production of cosmetic products in a concentration up to 0.2% by weight of raw materials.

Cosmetics Lavitol

Properties and fields of application of Cosmetic Lavitol

Dihydroquercetin has a wide range of pharmacological properties: antioxidant, capillaryprotective, anti-inflammatory, detoxification, radioprotective activity. All these activities support the use of Dihydroquercetin in the cosmetic industry.

Dihydroquercetin is a powerful antioxidant of a plant origin that can protect cells from the harmful effects caused by the excessive free radicals.

Dihydroquercetin reduces oxidative injury in human skin fibroblasts induced by glutathione depletion.

Dihydroquercetin inhibits the oxidation process in cosmetic products rich in oxidation-prone unsaturated fatty acids.

Cosmetic Lavitol® has the keratolytic effect. Moreover, Cosmetic Lavitol promotes cells renewal of epidermis, activates the regeneration process, has the pronounced moisture-retaining effect, enhances fibroplastic reaction that is testified to positive influence of Cosmetic Lavitol on water-electrolyte and protein metabolism in the skin and stimulating action on glycosaminoglycans synthesis responsible for moisture-retaining effect.

Cosmetic Lavitol® has the pronounced capillary-protective action, expressed in vascularization, strengthening of blood flow and improvement of skin nutrition. Cosmetic Lavitol decreases significantly the number of lymphahistiocytic elements, indicated the presence of immunomodulating effect which became apparent in regulation of local tissue immunity.

Quality

Ametis JSC produces the effective cosmetic substance under the trade mark Cosmetic Lavitol® with Dihydroquercetin (taxifolin) content over 88%.

Cosmetic Lavitol® is being produced by Ametis JSC in accordance with the Technical Requirements TY 9154-005-48375962-05.

Cosmetic Lavitol® is regularly analyzed in the accredited analytical laboratory of the enterprise (Certificate No POCC RU.0001.517430), as well as in the accredited testing analytical laboratory center based on the Public Health Federal State Establishment “Center for Hygiene and Epidemiology in Amur Region” and periodically analyzed by the Certification Center of Parfumery-Cosmetic Product & Services – Cosmetic Test (Moscow, Russia).

Lavitol (Dihydroquercetin)

Ametis JSC produces Lavitol (Dihydroquercetin) from the stumps of Dahurian Larch (Gmelinii Larch) that are grown in ecologically clean areas of the Amur Region. The use of ethyl alcohol as an extracting agent allows to receive a high quality product, used in food and nutritional industries.

The use of hi-tech equipments and its own patented technology for of the extraction allows to produce dihydroquercetin with 70 – 99.5% purity in industrial volumes. The monthly production volume of 99% Dihydroquercetin is 500 kg.

Lavitol (Dihydroquercetin) is the active antioxidant. Ametis JSC entrusted two independent laboratories with testing the antioxidative activity of Lavitol (Dihydroquercetin). The method of the Oxygen Radical Absorption Capacity of the dissolved in water product (ORAChydro) was used in the testing. The test results showed that Lavitol (Dihydroquercetin) has very high ORAC value, which exceeds that of some known antioxidants.

Dihydroquercetin acting as a substance with high level of biological activity, has positive effects on the metabolic reactions and the dynamics of various pathological processes and can be widely used in various industries.

Application of Dihydroquercetin

By the end of December 2013, over 300 products with dihydroquercetin were registered with the regulatory organs of the Russian Federation. Among these products, more than 200 were bioactive food supplements, over 40 food products, and approximately 80 cosmetic products.

The application of Dihydroquercetin is regulated by the following normative documentations in the Russian Federation:

  • The Methodical recommendations of the State Sanitary and Epidemiological Regulation No 2.3.1.1915-04 “Recommended norm of consumption of food and biologically active supplements” has determined the appropriate and the highest allowable level of Dihydroquercetin consumption: 25–100 mg per day.
  • According to the Decision of the State Chief Medical Officer dated 11/14/2001 No 36 “About the application of the Sanitary and Epidemiological Conclusion (SEC) 2.3.2.1078-01”, Dihydroquercetin is classified as an antioxidant;
  • The Decision of the State Chief Medical Officer dated 04/18/2003 No 59 “About the application of SEC 2.3.2.1293-03” allows using Dihydroquercetin for in manufacturing of cream, chocolate, and dry milk. The maximal content of Dihydroquercetin in these products is 200 mg/kg fat of the product;
  • The Technical Regulations of the customs Union 029/2012 allows using Dihydroquercetin as an antioxidant for manufacturing cream, dry milk, processed cheese, chocolate. The content of Dihydroquercetin in these products is 200 mg/kg fat of the product.